2024
- Clemens Mingels, Hande Nalbant, Hasan Sari, Felipe Godinez, Fatma Sen, Benjamin Spencer, Naseem S. Esteghamat, Joseph M. Tuscano, and Lorenzo Nardo. Long-axial field-of-view PET Imaging in Lymphoma Patients: Challenges and Opportunities. PET Clinics, Volume 19, Issue 4, 495 - 504; 2024.
Link: https://www.pet.theclinics.com/article/S1556-8598(24)00051-8/abstract
- Omidvari N, Levi J, Abdelhafez YG, Wang Y, Nardo L, Daly ME, Wang G, Cherry SR (2024) Total-body Dynamic Imaging and Kinetic Modeling of [18F]F-AraG in Healthy Individuals and a Non-Small Cell Lung Cancer Patient Undergoing Anti-PD-1 Immunotherapy. J Nucl Med;jnumed.123.267003.
- Siqi Li, Yansong Zhu, Benjamin A. Spencer, Guobao Wang. Single-Subject Deep-Learning Image Reconstruction with a Neural Optimization Transfer Algorithm for PET-enabled Dual-Energy CT Imaging. IEEE Transactions on Image Processing, vol. 33, pp. 4075-4089, 2024, doi: 10.1109/TIP.2024.3418347.
Link: https://ieeexplore.ieee.org/abstract/document/10577580 - Emily N. Holy, Elizabeth Li, Anjan Bhattarai, Evan Fletcher, Evelyn R. Alfaro, Danielle J. Harvey, Benjamin A. Spencer, Simon R. Cherry, Charles S. DeCarli, and Audrey P. Fan. Holy EN, Li E, Bhattarai A, Fletcher E, Alfaro ER, Harvey DJ, Spencer BA, Cherry SR, DeCarli CS, and Fan AP. Non-invasive quantification of 18F-florbetaben with total-body EXPLORER PET. EJNMMI Res. 14, 39 (2024). https://doi.org/10.1186/s13550-024-01104-7
Link: https://ejnmmires.springeropen.com/articles/10.1186/s13550-024-01104-7
- Bayerlein R, Selfridge A, Swarnakar V, Spencer BA and Badawi RD. Cloud-Based Serverless Computing Enables Accelerated Monte Carlo Simulations for Nuclear Medicine Imaging, BPEX, in press. PMID: 38876087 PMCID: PMC11254166 (available on 2025-06-25). DOI: 10.1088/2057-1976/ad5847
- Abdelhafez YG, Wang G, Li S, Chaudhari AJ, Ramirez A, Sen F, Sidossis LS, Klein S, Badawi RD and Chondronikola M. The Role of Brown Adipose Tissue in Branched-chain Amino Acid Clearance in People, iScience, in press
- Wang Q, Abdelhafez YG, Nalbant H, Spencer BA, Bayerlein R, Qi J, Cherry SR, Nardo L, and Badawi RD. Refining Penalty Parameter Selection in Whole-Body PET Image Reconstruction for Improved Diagnosis of Lung Cancer Patients using Cross-Validation Log-Likelihood Method
Phys. Med. Biol., in press
- Bayerlein R, Spencer BA, Leung EK, Omidvari N, Abdelhafez YG, Wang Q, Nardo L, Cherry SR and Badawi RD. Development of a Monte Carlo-Based Scatter Correction Method for Total-Body PET Using the uEXPLORER PET/CT Scanner
Phys. Med. Biol., in press
- Wang Y, Abdelhafez YG, Spencer BA, Verma R, Marikh M, Stollenwerk N, Nardo L, Jones T, Badawi RD, Cherry SR and Wang G. High-Temporal Resolution Kinetic Modeling of Lung Tumors with Dual-Blood Input Function Using Total-Body Dynamic PET, J. Nucl. Med., May 2024, 65 (5) 714-721; DOI: https://doi.org/10.2967/jnumed.123.267036. PMID: 38548347 PMCID: PMC11064825
- Mingels C, Spencer BA, Hande N, Rokni M, Omidvari N, Rominger A, Sen F, Badawi R, Abdelhafez YG and Nardo L. Dose Reduction and Short Acquisitions in Oncologic Pediatric Patients with Delayed Total-Body [18F]FDG PET/CT, J. Nucl. Med., in press
- Zhu Y, Tran Q, Wang Y, Badawi RD, Cherry SR, Qi J, Abbaszaddeh S and Wang G. Optimization-derived blood input function using a kernel method and its evaluation with total-body PET for brain parametric imaging.
NeuroImage, in press
- Li H, Badawi RD, Cherry SR, Fontaine K, He L, Henry S, Hu L, Jones T, Khattar N, Leung EK, Li T, Li Y, Liu P, Lu Z, Majewski S, Matuskey D, Mulnix T, Omidvari N, Samanta S, Selfridge A, Dun X, Toyonaga T, Volpi T, Zeng T, Qi J and Carson RE. Performance Characteristics of the NeuroEXPLORER, a Next-Generation Human Brain PET/CT Imager, J. Nucl. Med., in press.
2023
- Benjamin A. Spencer, Kristin McBride, Heather Hunt, Terry Jones, Simon R. Cherry and Ramsey D. Badawi. Practical considerations for total-body PET acquisition and imaging. Springer, Methods in Molecular Biology. In: Witney, T.H., Shuhendler, A.J. (eds) Positron Emission Tomography. Methods in Molecular Biology, vol 2729. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3499-8_21
Link: https://link.springer.com/protocol/10.1007/978-1-0716-3499-8_21
- Li S, Gong K, Badawi RD, Qi J, and Wang G. Neural KEM: A Kernel Method with Deep Coefficient Prior for PET Image Reconstruction. IEEE Trans Med. Imag. 2023, 42(3), 785-796, https://doi.org/10.1109/TMI.2022.3217543 PMID: 36288234 PMCID: PMC10081957
- Triumbari EKA, Ruffini V, Mingels C, Rmominger A, Alavi A, Panterl AR, Werner TJ, Badawi RD and Nardo L. Long axial field of view PET/CT can answer unmet needs in gynecological cancers Cancers 2023, 15(9), 2407; https://doi.org/10.3390/cancers15092407 PMID: 37173874 PMCID: PMC10177015
- Calabrò A, Abdelhafez YG , Triumbari EKA, Spencer BA, Chen MS Jr., Albano D, Cassim CR, Bertagna F, Dondi F, Cherry SR, Badawi RD, Sen F and Nardo L. 18F-FDG Gallbladder Uptake: Observation from a Total-Body PET/CT Scanner. BMC Medical Imaging. 23, 9, Jan 2023. https://doi.org/10.1186/s12880-022-00957-5. PMID: 36627570 PMCID: PMC9832624
- Wang Y, Spencer BA, Schmall J, Li E, Badawi RD, Jones T, Cherry SR and Wang G. High-Temporal Resolution Lung Kinetic Modeling Using Total-Body Dynamic PET with Dual-Blood Input and Dispersion Corrections J. Nucl. Med. April 2023. DOI: https://doi.org/10.2967/jnumed.122.264810 PMID: 37116916 PMCID: PMC10315691
- Sundar LKS, Lassen ML, Gutschmayer S, Ferrara D, Calabro A, Yu J, Wang Y, Nardo LN, Hasbak P, Abdelhafez AG, Wang G, Cherry SR, Spencer BA, Badawi RD, Beyer T and Muzik O. et al. Fully-automated, fast motion correction of dynamic total-body 18F-FDG PET/CT imaging studies. J. Nucl. Med. 64(7):1145-1153. July 2023 DOI: https://doi.org/10.2967/jnumed.122.265362. PMID: 37290795 Epub ahead of print: June 8th, 2023
- Selfridge AR, Spencer BA, Abdelhafez YG, Nakagawa K, Tupin J and Badawi RD. Facial anonymization and privacy concerns in total-body PET/CT J. Nucl. Med. Aug 2023. 64(8) 1304-1309. DOI: https://doi.org/10.2967/jnumed.122.265280. PMID: 37268426 PMCID: PMC10394314
- Wang Y, Nardo L, Spencer BA, Abdelhafez YG, Chaudhari AJ, Badawi RD, Jones T, Cherry SR and Wang G. Total-Body Multiparametric Quantification of 18F-FDG Delivery and Metabolism in the study of Coronavirus Disease 2019 Recovery. J. Nucl. Med.. 64 (11) 1821-1830; November 2023. DOI: https://doi.org/10.2967/jnumed.123.265723. PMID: 37591539 PMCID: PMC10626370
- Bayerlein R, Spencer BA, Abdelhafez YG, Cherry SR, Badawi RD and Omidvari N. Numerical Investigation Reveals Challenges in Measuring the Contrast Recovery Coefficients in PET Phys. Med. Biol. 68 (21). Oct 2023;. DOI: 10.1088/1361-6560/ad00fa PMID: 37802064
- Li EJ, Lopez J, Spencer BA, Abdelhafez YG, Badawi RD, Wang G and Cherry SR. Total-Body Perfusion Imaging with [11C]-Butanol. J. Nucl. Med. 64(11):1831-1838. November 2023. DOI: 10.2967/jnumed.123.265659. PMID: 37652544 PMCID: PMC10626376
- Omidvari N, Jones T, Price PM, Ferre AL, Lu J, Abdelhafez YG, Sen F, Cohen S, Badawi RD, Shacklett BL, Wilson I and Cherry SR. First-in-human immunoPET imaging of COVID-19 convalescent patients using dynamic total-body PET and a CD8-targeted minibody, Science Advances. 9 (41). Oct 2023. DOI: 10.1126/sciadv.adh7968; PMID: 3782461; PMCID: PMC10569706
2022
- Ng QKT, Triumbari EKA, Omidvari N, Cherry SR, Badawi RD and Nardo L. Total-body PET/CT – first clinical experiences and future perspectives. Seminars in Nuclear Medicine, 52 (3), May 2022,330-339. DOI: https://doi.org/10.1053/ j.semnuclmed.2022.01.002. PMID: 35272853 PMCID: PMC9439875
- Leung EK, Berg E, Abdelhafez YG, Spencer BA, Jones T, Cherry SR and Badawi RD. Relating 18F-FDG image signal-to-noise ratio to time-of-flight noise-equivalent count rate in total-body PET using the uEXPLORER scanner
Phys. Med. Biol. 67 125007. 2022 June 10. https://doi.org/10.1088/1361-6560/ac72f1 . PMID: 35609588 PMCID: PMC9275089
- Abdelhafez YG, McBride K, Leung EK, Hunt HL, Spencer BA, Lopez JE, Atsina K, Li EJ, Wang G, Cherry SR, Badawi RD, Sen F and Nardo L. Blanching Defect at the Pressure Points: Observations from Dynamic Total-Body PET/CT Studies
J. Nucl Med. Tech. December 2022, 50 (4) 327-334; DOI: https://doi.org/10.2967/jnmt.122.263905. PMID: 35440473 PMCID: PMC9745988
- Abdelhafez YG, Raychaudhuri SP, Mazza D, Sarkar S, Hunt HL, McBride K, Nguyen M, Caudle DT, Spencer BA, Omidvari N, Bang H, Cherry SR, Nardo L, Badawi RD and Chaudhari AJ. Total-Body 18F-FDG PET/CT in Autoimmune Inflammatory Arthritis at Ultra-Low Dose: Initial Observations
J. Nucl. Med, October 2022, 63 (10) 1579-1585; DOI: https://doi.org/10.2967/jnumed.121.263774. PMID: 35589405 PMCID: PMC9536697
- Omidvari N, Cheng L, Leung EK, Abdelhafez YG, Badawi RD, Ma T, Qi J and Cherry SR. Lutetium Background Radiation in Total-Body PET – A Simulation Study on Opportunities and Challenges in PET Attenuation Correction
Frontiers in Nuclear Medicine. 2022 Aug 10; https://doi.org/10.3389/fnume.2022.963067.PMID: 36172601 PMCID: PMC9513593
- Sundar LKS, Yu J, Muzik O, Kulterer O, Fueger B, Kifjak D, Nakuz T, Shin HM, Sima AK, Kitzmantl D, Badawi RD, Nardo L, Cherry SR, Spencer BA, Hacker M and Beyer T. Fully-automated, semantic segmentation of whole-body 18F-FDG PET/CT images based on data-centric artificial intelligence. J. Nucl Med. 2022 December 2022, 63 (12) 1941-1948; https://doi.org/10.2967/jnumed.122.264063. PMID: 35772962
- Derlin T, Spencer BA, Mamach M, Abdelhafez YG, Nardo L, Badawi RD, Cherry SR and Bengel FM. Exploring Vessel Wall Biology In Vivo By Ultra-Sensitive Total-Body PET J. Nucl. Med. Epub ahead of print. PMID: 36175139 PMCID: PMC10071799
2021
- Sarkar S, Matsukuma K, Spencer B, Chen S, Olson KA, Badawi RD, Corwin MT and Wang G. Dynamic 18F-Fluorodeoxyglucose PET correlate of liver inflammation in Nonalcoholic Steatohepatitis
Clinical Gastroenterology and Hepatology 2021;19 (11):2441–2443. https://doi.org/10.1016/j.cgh.2020.10.029
- Elizabeth Li, Benjamin A. Spencer, Jeffrey P. Schmall, Yasser Abdelhafez, Ramsey D. Badawi, Guobao Wang and Simon R. Cherry,
Efficient delay correction for total-body PET kinetic modeling using pulse timing methods,
Journal of Nuclear Medicine, December 2021, jnumed.121.262968.
- Guobao Wang, Lorenzo Nardo, Mamta Parikh, Yasser G. Abdelhafez, Elizabeth Li, Benjamin A. Spencer, Jinyi Qi, Terry Jones, Simon R. Cherry and Ramsey D. Badawi
Total-Body PET Multiparametric Imaging of Cancer Using a Voxel-wise Strategy of Compartmental Modeling
Journal of Nuclear Medicine, November 2021, jnumed.121.262668.
- Gustavo Coelho Alves Costa, Benjamin A. Spencer, Negar Omidvari, Cameron Foster, Michael Rusnak, Heather Hunt, Denise T Caudle, Rex Pillai, Catherine Vu and Emilie Roncali
Radioembolization Dosimetry with Total-Body 90Y PET
Journal of Nuclear Medicine, November 2021, jnumed.121.263145.
- Edwin K. Leung, Eric Berg, Negar Omidvari, Benjamin A. Spencer, Elizabeth Li, Yasser G. Abdelhafez, Jeffrey P. Schmall, Weiping Liu, Liuchun He, Songsong Tang, Y. Liu, Yun Dong, Terry Jones, Simon R. Cherry, Ramsey D. Badawi
Quantitative accuracy in total-body imaging using the uEXPLORER PET/CT scanner
Physics in Medicine and Biology, 66(20): 205008, 2021.
- Yiran Wang, Elizabeth Li, Simon R. Cherry, and Guobao Wang
Total-Body PET Kinetic Modeling and Potential Opportunities Using Deep Learning
PET Clin., 2021 Oct;16(4):613-625. doi: 10.1016/j.cpet.2021.06.009.
- Jinyi Qi, Samuel Matej, Guobao Wang, and Xuezhu Zhang
3D/4D Reconstruction and Quantitative Total Body Imaging
PET Clin., 2021 Jan;16(1):41-54. doi: 10.1016/j.cpet.2020.09.008.
- Lorenzo Nardo, Yasser G. Abdelhafez, Benjamin A. Spencer and Ramsey D Badawi
Clinical Implementation of Total-body PET/CT at University of California, Davis
PET Clin., 2021 Jan;16(1):1-7. doi: 10.1016/j.cpet.2020.09.006.
2020
- Benjamin A. Spencer*, Eric Berg*, Jeffrey P. Schmall, Negar Omidvari, Edwin K. Leung, Yasser G. Abdelhafez, Songsong Tang, Zilin Deng, Yun Dong, Yang Lv, Jun Bao, Weiping Liu, Hongdi Li, Terry Jones, Ramsey D. Badawi, and Simon R. Cherry (* authors contributed equally)
Performance evaluation of the uEXPLORER Total-body PET/CT scanner based on NEMA NU 2-2018 with additional tests to characterize long axial field-of-view PET scanners
Journal of Nuclear Medicine, October 2020, jnumed.120.250597.
- Eric Berg, Herman Gill, Jan Marik, Annie Ogasawara, Simon Williams, Guus van Dongen, Daniëlle Vugts, Simon R Cherry, and Alice F Tarantal
Total-Body PET and Highly Stable Chelators Together Enable Meaningful 89 Zr-Antibody PET Studies up to 30 Days After Injection
Journal of Nuclear Medicine, 2020; 61:453–460.
- Xuezhu Zhang, Simon R. Cherry, Zhaoheng Xie, Hongcheng Shi, Ramsey D. Badawi, and Jinyi Qi.
Subsecond total-body imaging using ultrasensitive positron emission tomography
Proceedings of the National Academy of Sciences, 117, no. 5 (2020): 2265-2267.
- Xuezhu Zhang, Zhaoheng Xie, Eric Berg, Martin S. Judenhofer, Weiping Liu, Tianyi Xu, Yu Ding, Yang Lv, Yun Dong, Zilin Deng, Songsong Tang, Hongcheng Shi, Pengcheng Hu, Shuguang Chen, Jun Bao, Hongdi Li, Jian Zhou, Guobao Wang, Simon R. Cherry, Ramsey D. Badawi, and Jinyi Qi
Total-body dynamic reconstruction and parametric imaging on the uEXPLORER
Journal of Nuclear Medicine, 2020; 61:285–291.
2019
- Ramsey D. Badawi, Hongcheng Shi, Pengcheng Hu, Shuguang Chen, Tianyi Xu, Patricia M. Price, Yu Ding, Benjamin A. Spencer, Lorenzo Nardo1, Weiping Liu, Jun Bao, Terry Jones, Hongdi Li and Simon R. Cherry
First Human Imaging Studies with the EXPLORER Total-Body PET Scanner
Journal of Nuclear Medicine, 2019; 60:299–303.
- Yang Lv, Xinyu Lv, Weiping Liu, Martin S Judenhofer, Allison Zwingenberger, Erik Wisner, Eric Berg, Sarah McKenney, Edwin Leung, Benjamin A Spencer, Simon R Cherry, and Ramsey D Badawi
Mini EXPLORER II: A Prototype High-sensitivity PET/CT Scanner for Companion Animal and Human Brain Scanning
Physics in Medicine and Biology, 64(7): 075004, 2019.
2018
- Edwin K. Leung, Martin S. Judenhofer, Simon R. Cherry and Ramsey D. Badawi
Performance assessment of a software-based coincidence processor for the EXPLORER total-body PET scanner
Physics in Medicine and Biology, 63(18): 18NT01, 2018.
- Simon R. Cherry, Terry Jones, Joel S. Karp, Jinyi Qi, William W. Moses, Ramsey D. Badawi,
Total-Body PET: Maximizing Sensitivity to Create New Opportunities for Clinical Research and Patient Care
Journal of Nuclear Medicine, 2018; 59:3–12
2017
- Simon R. Cherry, Ramsey D. Badawi, Joel S. Karp, William W. Moses, Pat Price, Terry Jones
Total-body imaging: Transforming the role of positron emission tomography
Sci. Transl. Med., Vol. 9, Issue 381, eaaf6169 (2017).
- Xuezhu Zhang, Jian Zhou, Simon R. Cherry, Ramsey D. Badawi, Jinyi Qi
Quantitative image reconstruction for total-body PET imaging using the 2-meter long EXPLORER scanner
Physics in Medicine and Biology, 62 (2017) pp. 2465–2485
2016
- Jeffrey P. Schmall, Joel S. Karp, Matt Werner, Suleman Surti
Parallax error in long-axial field-of-view PET scanners – a simulation study
Physics in Medicine and Biology, 61 (2016) pp. 5443–5455
2015
- Suleman Surti, Joel S. Karp
Impact of detector design on imaging performance of a long axial field-of-view, whole-body PET scanner
Physics in Medicine and Biology, 60 (2015) pp. 5343–5358|
- Pat Price, Ramsey D. Badawi, Simon R. Cherry, Terry Jones
Ultra-staging to unmask the prescribing of adjuvant therapy in cancer patients: the future opportunity to image micro-metastases using total body 18FDG-PET scanning
Journal of Nuclear Medicine, 2014; 55:696-697
2012
- Jonathan K. Poon, Magnus L. Dahlbom, William W. Moses, Karthik Balakrishnan, Wenli Wang, Simon R. Cherry, Ramsey D. Badawi
Optimal whole-body PET scanner configurations for different volumes of LSO scintillator: a simulation study
Physics in Medicine and Biology, 57 (2012) pp. 4077–4094
2006
- Simon R. Cherry
The 2006 Henry N. Wagner Lecture: Of Mice and Men (and Positrons) – Advances in PET imaging technology
Journal of Nuclear Medicine, 2006; 47:1735–1745